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med64 recording system  (Panasonic Healthcare)


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    Panasonic Healthcare med64 recording system
    Med64 Recording System, supplied by Panasonic Healthcare, used in various techniques. Bioz Stars score: 94/100, based on 104 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/med64+recording+system/MED64+Multi-electrode+Array+System/pmc12171265-39-2-5
    Average 94 stars, based on 104 article reviews
    med64 recording system - by Bioz Stars, 2026-09
    94/100 stars

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    Article Title: Recruitment of cortical silent responses by forskolin in the anterior cingulate cortex of adult mice
    Article Snippet: A commercial MED64 recording system (Panasonic) was used for extracellular field potential recordings.

    Article Title: Characterization of excitatory synaptic transmission in the retrosplenial cortex of adult mice
    Article Snippet: A commercial MED64 recording system (Panasonic) was used for extracellular field potential recordings.

    Article Title: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease
    Article Snippet: The MED64 recording system (Panasonic, Japan) was used for extracellular field potential recordings.

    Article Title: Characterization of excitatory synaptic transmission in the retrosplenial cortex of adult mice.
    Article Snippet: A commercial MED64 recording system (Panasonic) was used for extracellular field potential recordings.

    Article Title: Praeruptorin C alleviates cognitive impairment in type 2 diabetic mice through restoring PI3K/AKT/GSK3β pathway.
    Article Snippet: Funding information National Natural Science Foundation of China, Grant/Award Numbers: 31800887, 31972902, 82071515; Young Talent Fund of University Association for Science and Technology in Shaanxi, China, Grant/Award Number: 20200307 Abstract Diabetic encephalopathy is a common consequence of diabetes mellitus that causes cognitive dysfunction and neuropsychiatric disorders.. Praeruptorin C (Pra-C) from the traditional Chinese medicinal herb Peucedanum praeruptorum Dunn. is a potential antioxidant and neuroprotective agent.. This study was conducted to investigate the molecular mechanisms underlying the effect of Pra-C on diabetic cognitive impairment.

    Article Title: Inhibition of calcium-stimulated adenylyl cyclase subtype 1 (AC1) for the treatment of neuropathic and inflammatory pain in adult female mice
    Article Snippet: The MED64 recording system (Panasonic, Japan) was used for extracellular field potential recordings.

    Article Title: Praeruptorin C alleviates cognitive impairment in Type 2 diabetic mice through restoring PI3K/AKT/ GSK3β pathway
    Article Snippet: A commercial MED64 recording system (Panasonic Alpha-Med Sciences, Osaka, Japan) was used to record eld excitatory postsynaptic potentials (fEPSPs), and the procedure was similar to previous study [27].

    Article Title: Recruitment of cortical silent responses by forskolin in the anterior cingulate cortex of adult mice.
    Article Snippet: Slices were transferred to a submerged recovery chamber with 12 oxygenated (95% O2 and 5% CO2) ACSF at room temperature for at least 1 h. 13 14 Preparation of the multielectrode array 15 A commercial MED64 recording system (Panasonic) was used for extracellular field potential 16 recordings.



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    Schematic diagram of the <t>MED64</t> P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the <t>multichannel</t> probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.
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    Panasonic Healthcare med64 recording system
    Schematic diagram of the <t>MED64</t> P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the <t>multichannel</t> probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.
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    Schematic diagram of the <t>MED64</t> P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the <t>multichannel</t> probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.
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    Schematic diagram of the <t>MED64</t> P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the <t>multichannel</t> probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.
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    Schematic diagram of the MED64 P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the multichannel probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.

    Journal: PLOS Biology

    Article Title: Supraspinal facilitation of painful stimuli by glutamatergic innervation from the retrosplenial to the anterior cingulate cortex

    doi: 10.1371/journal.pbio.3003011

    Figure Lengend Snippet: Schematic diagram of the MED64 P5001A probe (three-group arrays including 64 50 × 50-μm planar microelectrodes with 150 μm apart from each other). (B) Schematic diagram showing the relative position between the multichannel probe and the sagittal brain slice. The fEPSPs of RSC and ACC regions are recorded respectively by Group 1 (G1) and Group 2 (G2) electrode arrays with the stimulus site (red) in the RSC. (C, D) The example of recorded fEPSPs from the RSC (18 channels) and ACC (21 channels) with one stimulus channel (red line) in the RSC. The numbers 1–3 represent different types of channels (the active, the silent, and abnormal channels, respectively). (E) The pie chart showing the percentage of 3 types of the recorded channels in the RSC and ACC, respectively (RSC: type 1 = 79.37%, type 2 = 17.46%, type 3 = 3.17%; ACC: type 1 = 63.95%, type 2 = 35.37%, type 3 = 0.68%, n = 7 slices from 5 mice). (F) The averaged amplitude of all the recorded fEPSCs from the RSC and ACC in each brain slice (two-tailed unpaired t test: t = 5.314, *** p < 0.0001, n = 8 slices from 5 mice). The summary data for Fig 2 can be found in . ACC, anterior cingulate cortex; RSC, retrosplenial cortex.

    Article Snippet: Here, we first performed the multichannel field potential recording (MED64) to record the field excitatory postsynaptic potentials (fEPSPs) in the ACC with the electrical stimulus in the RSC on the sagittal brain slice ( ).

    Techniques: Slice Preparation, Two Tailed Test